Timing of captopril administration determines radiation protection or radiation sensitization in a murine model of total body irradiation
نویسندگان
چکیده
or radiation sensitization in a murine model of total body irradiation Thomas A. Davis, Michael R. Landauer, Steven R. Mog, Michal Barshishat-Kupper, Stephen R. Zins, Mihret F. Amare, and Regina M. Day Department of Regenerative Medicine, Naval Medical Research Center, Silver Spring, Md., USA; Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Md., USA; Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, Md., USA
منابع مشابه
Re: Davis et al., "Timing of captopril administration determines radiation protection or radiation sensitization in a murine model of total body irradiation".
OBJECTIVE Angiotensin II (Ang II), a potent vasoconstrictor, affects the growth and development of hematopoietic cells. Mixed findings have been reported for the effects of angiotensin-converting enzyme (ACE) inhibitors on radiation-induced injury to the hematopoietic system. We investigated the consequences of different regimens of the ACE inhibitor captopril on radiation-induced hematopoietic...
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